Chemoimmunotherapy With a Modified Hyper-CVAD and Rituximab Regimen Improves Outcome in De Novo Philadelphia Chromosome–Negative Precursor B-Lineage Acute Lymphoblastic Leukemia

PURPOSE: The adverse prognosis of CD20 expression in adults with de novo precursor B-lineage acute lymphoblastic leukemia (ALL) prompted incorporation of monoclonal antibody therapy with rituximab into the intensive chemotherapy regimen hyper-CVAD (fractionated cyclophosphamide, vincristine, doxorub...

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Main Authors: Thomas, Deborah A., O'Brien, Susan, Faderl, Stefan, Garcia-Manero, Guillermo, Ferrajoli, Alessandra, Wierda, William, Ravandi, Farhad, Verstovsek, Srdan, Jorgensen, Jeffrey L., Bueso-Ramos, Carlos, Andreeff, Michael, Pierce, Sherry, Garris, Rebecca, Keating, Michael J., Cortes, Jorge, Kantarjian, Hagop M.
格式: Artigo
語言:Inglês
出版: American Society of Clinical Oncology 2010
主題:
Original Reports
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940403/
https://ncbi.nlm.nih.gov/pubmed/20660823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2009.26.9456
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