Effects of the EGFR Inhibitor Erlotinib on Magnesium Handling

A mutation in pro-EGF causes isolated hypomagnesemia, and monoclonal antibodies targeting the extracellular domain of the EGF receptor (EGFR) affect epithelial Mg(2+) transport. The effect of the EGFR tyrosine kinase inhibitor erlotinib on Mg(2+) homeostasis, however, remains unknown. Here, we injec...

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Bibliographic Details
Main Authors:	Dimke, Henrik, van der Wijst, Jenny, Alexander, Todd R., Meijer, Inez M.J., Mulder, Gemma M., van Goor, Harry, Tejpar, Sabine, Hoenderop, Joost G., Bindels, René J.
Format:	Artigo
Language:	Inglês
Published:	American Society of Nephrology 2010
Subjects:	Basic Research
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2938592/ https://ncbi.nlm.nih.gov/pubmed/20595681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009111153
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Effects of the EGFR Inhibitor Erlotinib on Magnesium Handling

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