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Human β(1)-Adrenergic Receptor Is Subject to Constitutive and Regulated N-terminal Cleavage

The β(1)-adrenergic receptor (β(1)AR) is the predominant βAR in the heart, mediating the catecholamine-stimulated increase in cardiac rate and force of contraction. Regulation of this important G protein-coupled receptor is nevertheless poorly understood. We describe here the biosynthetic profile of...

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Main Authors: Hakalahti, Anna E., Vierimaa, Miia M., Lilja, Minna K., Kumpula, Esa-Pekka, Tuusa, Jussi T., Petäjä-Repo, Ulla E.
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937912/
https://ncbi.nlm.nih.gov/pubmed/20587416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.149989
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