A novel quinone-based derivative (DTNQ-Pro) induces apoptotic death via modulation of heat shock protein expression in Caco-2 cells

BACKGROUND AND PURPOSE: The resistance of human colon adenocarcinoma cells to antineoplastic agents may be related to the high endogenous expression of stress proteins, including the family of heat shock proteins (HSPs). Recently, a quinone-based pentacyclic derivative, DTNQ-Pro, showed high cytotox...

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Главные авторы: Gomez-Monterrey, Isabel, Campiglia, Pietro, Bertamino, Alessia, Aquino, Claudio, Sala, Marina, Grieco, Paolo, Dicitore, Alessandra, Vanacore, Daniela, Porta, Amalia, Maresca, Bruno, Novellino, Ettore, Stiuso, Paola
Формат: Artigo
Язык:Inglês
Опубликовано: Blackwell Publishing Ltd 2010
Предметы:
Research Papers
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935999/
https://ncbi.nlm.nih.gov/pubmed/20590589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.00718.x
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