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Notch1 Is Required for Maintenance of the Reservoir of Adult Hippocampal Stem Cells
Notch1 regulates neural stem cell (NSC) number during development, but its role in adult neurogenesis is unclear. We generated nestin-CreER(T2)/R26R-YFP/Notch1(loxP/loxP) [Notch1inducible knock-out (iKO)] mice to allow tamoxifen (TAM)-inducible elimination of Notch1 and concomitant expression of yel...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Society for Neuroscience
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2935844/ https://ncbi.nlm.nih.gov/pubmed/20685991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4721-09.2010 |
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