Expression of the PAX8/PPARγ Fusion Protein Is Associated with Decreased Neovascularization In Vivo: Impact on Tumorigenesis and Disease Prognosis

The PAX8/PPARγ fusion protein (PPFP) occurs in 36% of human follicular thyroid carcinoma (FTC) and is associated with favorable prognosis. To elucidate the function of PPFP in FTC, we analyzed the consequences of PPFP expression in immortalized thyrocytes in vitro and in vivo via xenograft tumorigen...

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Главные авторы: Reddi, H.V., Madde, P., Marlow, L.A., Copland, J.A., McIver, B., Grebe, S.K.G., Eberhardt, N.L.
Формат: Artigo
Язык:Inglês
Опубликовано: SAGE Publications 2010
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Original Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934914/
https://ncbi.nlm.nih.gov/pubmed/20827445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601910373545
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