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High-yield bacterial expression and structural characterization of recombinant human insulin-like growth factor binding protein-2
The diverse biological activities of the insulin-like growth factors (IGF-1 and IGF-2) are mediated by the IGF-1 receptor (IGF-IR). These actions are modulated by a family of six IGF-binding proteins (IGFBP-1–6; 22–31 kDa) that via high affinity binding to the IGFs (K(D) ~ 300–700 pM) both protect t...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2934857/ https://ncbi.nlm.nih.gov/pubmed/20541521 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2010.06.006 |
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