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Of Extracellular Matrix, Scaffolds, and Signaling: Tissue Architecture Regulates Development, Homeostasis, and Cancer

The microenvironment influences gene expression so that the behavior of a cell is largely determined by its interactions with the extracellular matrix, neighboring cells, and soluble local and systemic cues. We describe the essential roles of context and organ structure in directing mammary gland de...

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Main Authors: Nelson, Celeste M., Bissell, Mina J.
格式: Artigo
語言:Inglês
出版: 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933192/
https://ncbi.nlm.nih.gov/pubmed/16824016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev.cellbio.22.010305.104315
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