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Regulation of Notch1 Signaling by Nrf2: Implications for Tissue Regeneration
The Keap1-Nrf2-ARE signaling pathway evokes an adaptive response for cell survival following endogenous (for example, inflammation) and exogenous (for example, carcinogens) stresses. Keap1 inhibits the transcriptional activation activity of Nrf2 in unstressed cells by facilitating its degradation. T...
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| Huvudupphovsmän: | , , , , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2010
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2932745/ https://ncbi.nlm.nih.gov/pubmed/20628156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2000762 |
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