Similar hypercoagulable state and thrombosis risk in type I and type III protein S-deficient individuals from families with mixed type I/III protein S deficiency

BACKGROUND: Protein S, which circulates in plasma in both free and bound forms, is an anticoagulant protein that stimulates activated protein C and tissue factor pathway inhibitor. Hereditary type I protein S deficiency (low total and low free protein S) is a well-established risk factor for venous...

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Hlavní autoři: Castoldi, Elisabetta, Maurissen, Lisbeth F.A., Tormene, Daniela, Spiezia, Luca, Gavasso, Sabrina, Radu, Claudia, Hackeng, Tilman M., Rosing, Jan, Simioni, Paolo
Médium: Artigo
Jazyk:Inglês
Vydáno: Ferrata Storti Foundation 2010
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930959/
https://ncbi.nlm.nih.gov/pubmed/20421270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2010.021923
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