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Lower Brain-Derived Neurotrophic Factor in Patients with Prader-Willi Syndrome Compared to Obese and Lean Control Subjects

Context: Brain-derived neurotrophic factor (BDNF) haploinsufficiency is associated with hyperphagia and obesity in both animals and humans. BDNF appears to function downstream of the leptin-melanocortin signaling pathway to control energy balance. The potential role of BDNF in the etiology of the se...

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Autori principali: Han, Joan C., Muehlbauer, Michael J., Cui, Huaxia N., Newgard, Christopher B., Haqq, Andrea M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Endocrine Society 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928902/
https://ncbi.nlm.nih.gov/pubmed/20427492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2010-0127
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