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High-throughput proteomic analysis of formalin-fixed paraffin-embedded tissue microarrays using MALDI imaging mass spectrometry
A novel method for high-throughput proteomic analysis of formalin-fixed paraffin-embedded (FFPE) tissue microarrays (TMA) is described using on-tissue tryptic digestion followed by MALDI imaging MS. A TMA section containing 112 needle core biopsies from lung-tumor patients was analyzed using MS and...
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Hauptverfasser: | , , , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
2008
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2927989/ https://ncbi.nlm.nih.gov/pubmed/18712763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.200800495 |
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