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Fine tuning chemotherapy to match BRCA1 status

Targeted cancer therapies have been primarily directed at inhibiting oncogenes that are overexpressed or constitutively active in tumors. It is thought that as the cell’s circuitry gets rewired by the constitutive activation of some pathways it becomes exquisitely dependent on this activity. Tumor c...

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Dettagli Bibliografici
Autori principali: Price, Melissa, Monteiro, Alvaro N.A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925507/
https://ncbi.nlm.nih.gov/pubmed/20510205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2010.05.015
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