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Isolation of viable Plasmodium falciparum merozoites to define erythrocyte invasion events and advance vaccine and drug development

During blood-stage infection by Plasmodium falciparum, merozoites invade RBCs. Currently there is limited knowledge of cellular and molecular invasion events, and no established assays are available to readily measure and quantify invasion-inhibitory antibodies or compounds for vaccine and drug stud...

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Главные авторы: Boyle, Michelle J., Wilson, Danny W., Richards, Jack S., Riglar, David T., Tetteh, Kevin K. A., Conway, David J., Ralph, Stuart A., Baum, Jake, Beeson, James G.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922570/
https://ncbi.nlm.nih.gov/pubmed/20660744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009198107
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