Factor Xa induces tissue factor expression in endothelial cells by P44/42 MAPK and NF-κB-dependent pathways

BACKGROUND: Tissue factor (TF) is an initiator of coagulation. The serine protease factor Xa (FXa) is the convergence point of the extrinsic and intrinsic components of the coagulation cascade. In addition to its hemostatic function, FXa elicits inflammatory responses in endothelial cells that may b...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Jiang, Rong, Wang, Ning-Ping, Tanaka, Kenichi A., Levy, Jerrold H., Guyton, Robert A., Zhao, Zhi-Qing, Vinten-Johansen, Jakob
Formato: Artigo
Idioma:Inglês
Publicado: 2010
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920361/
https://ncbi.nlm.nih.gov/pubmed/20451919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2010.01.041
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares