Factor Xa induces tissue factor expression in endothelial cells by P44/42 MAPK and NF-κB-dependent pathways

BACKGROUND: Tissue factor (TF) is an initiator of coagulation. The serine protease factor Xa (FXa) is the convergence point of the extrinsic and intrinsic components of the coagulation cascade. In addition to its hemostatic function, FXa elicits inflammatory responses in endothelial cells that may b...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Jiang, Rong, Wang, Ning-Ping, Tanaka, Kenichi A., Levy, Jerrold H., Guyton, Robert A., Zhao, Zhi-Qing, Vinten-Johansen, Jakob
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920361/
https://ncbi.nlm.nih.gov/pubmed/20451919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2010.01.041
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg