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Insights into the mechanism of Rad51 recombinase from the structure and properties of a filament interface mutant

Rad51 protein promotes homologous recombination in eukaryotes. Recombination activities are activated by Rad51 filament assembly on ssDNA. Previous studies of yeast Rad51 showed that His352 occupies an important position at the filament interface, where it could relay signals between subunits and ac...

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Bibliografske podrobnosti
Main Authors: Chen, Jianhong, Villanueva, Nicolas, Rould, Mark A., Morrical, Scott W.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919713/
https://ncbi.nlm.nih.gov/pubmed/20371520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq209
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