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Altered structural fluctuations in duplex RNA versus DNA: a conformational switch involving base pair opening
DNA and RNA are known to have different structural properties. In the present study, molecular dynamics (MD) simulations on a series of RNA and DNA duplexes indicate differential structural flexibility for the two classes of oligonucleotides. In duplex RNA, multiple base pairs experienced local open...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2003
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC291876/ https://ncbi.nlm.nih.gov/pubmed/14654688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg941 |
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