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Biocatalytic asymmetric formation of tetrahydro-β-carbolines

Strictosidine synthase triggers the formation of strictosidine from tryptamine and secologanin, thereby generating a carbon-carbon bond and a new stereogenic center. Strictosidine contains a tetrahydro-β-carboline moiety − an important N-heterocyclic framework found in a range of natural products an...

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Autors principals: Bernhardt, Peter, Usera, Aimee R., O'Connor, Sarah E.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913883/
https://ncbi.nlm.nih.gov/pubmed/20689670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2010.06.075
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