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Total Synthesis of (−)-Lycoperine A

[Image: see text] Lycoperine A was synthesized through a highly convergent route in which a double alkylation of 2,6-dicyano-N-benzylpiperidine with the octahydroquinoline moiety gave the lycoperine skeleton. The octahydroquinoline was prepared by a desymmetrization reaction of 5-methylcyclohexane-1...

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Detalhes bibliográficos
Main Authors: Nakamura, Yoshitaka, Burke, Anthony M., Kotani, Shunsuke, Ziller, Joseph W., Rychnovsky, Scott D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913050/
https://ncbi.nlm.nih.gov/pubmed/19947619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol902389e
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