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Sequence-Based Analysis of Protein Energy Landscapes Reveals Nonuniform Thermal Adaptation within the Proteome

Thermal adaptation of individual proteins is often achieved through modulating protein stability, with proteins that are adapted to extreme cold environments having increased conformational flexibility when brought to mesophilic conditions. Conversely, proteins adapted to higher temperatures appear...

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Hlavní autoři: Gu, Jenny, Hilser, Vincent J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912464/
https://ncbi.nlm.nih.gov/pubmed/19592668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msp140
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