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Identification of Novel Synthetic Toll-like Receptor 2 Agonists by High Throughput Screening
Toll-like receptors (TLRs) play a central role in host defense by inducing inflammatory and adaptive immune responses following infection. Drugs that target TLRs are of considerable interest as potential inflammatory regulators, vaccine adjuvants, and novel immunotherapeutics. TLR2, in cooperation w...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2911294/ https://ncbi.nlm.nih.gov/pubmed/20504771 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.116046 |
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