Embryonic vascular endothelial cells are malleable to reprogramming via Prox1 to a lymphatic gene signature

BACKGROUND: In vivo studies demonstrate that the Prox1 transcription factor plays a critical role in the development of the early lymphatic system. Upon Prox1 expression, early lymphatic endothelial cells differentiate from the cardinal vein and begin to express lymphatic markers such as VEGFR-3, LY...

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Bibliographic Details
Main Authors: Kim, Harold, Nguyen, Vicky PKH, Petrova, Tatiana V, Cruz, Maribelle, Alitalo, Kari, Dumont, Daniel J
Format: Artigo
Language:Inglês
Published: BioMed Central 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909156/
https://ncbi.nlm.nih.gov/pubmed/20584329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-213X-10-72
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