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Cell-based multiscale computational modeling of small molecule absorption and retention in the lungs

PURPOSE: For optimizing the local, pulmonary targeting of inhaled medications, it is important to analyze the relationship between the physicochemical properties of small molecules and their absorption, retention and distribution in the various cell types of the airways and alveoli. METHODS: A compu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yu, Jing-yu, Rosania, Gus R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2907074/
https://ncbi.nlm.nih.gov/pubmed/20099073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-009-0034-9
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