I-Motif Structures Formed in the Human c-MYC Promoter Are Highly Dynamic–Insights into Sequence Redundancy and I-Motif Stability

The GC-rich nuclease hypersensitivity element III(1) (NHE III(1)) of the c-MYC promoter largely controls the transcriptional activity of the c-MYC oncogene. The C-rich strand in this region can form I-motif DNA secondary structures. We determined the folding pattern of the major I-motif formed in th...

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Hlavní autoři: Dai, Jixun, Hatzakis, Emmanuel, Hurley, Laurence H., Yang, Danzhou
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2010
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906509/
https://ncbi.nlm.nih.gov/pubmed/20657837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011647
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