Cloning of a salivary gland metalloprotease and characterization of gelatinase and fibrin(ogen)lytic activities in the saliva of the Lyme Disease tick vector Ixodes scapularis

The full-length sequence of tick salivary gland cDNA coding for a protein similar to metalloproteases (MP) of the reprolysin family is reported. The Ixodes scapularis MP is a 488 aminoacid (aa) protein containing pre- and pro-enzyme domains, the zinc-binding motif HExxHxxGxxH common to metalloprotea...

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Bibliographic Details
Main Authors: Francischetti, Ivo M. B., Mather, Thomas N., Ribeiro, José M. C.
Format: Artigo
Language:Inglês
Published: 2003
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903890/
https://ncbi.nlm.nih.gov/pubmed/12767911
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