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Calflagin Inhibition Prolongs Host Survival and Suppresses Parasitemia in Trypanosoma brucei Infection

African trypanosomes express a family of dually acylated, EF-hand calcium-binding proteins called the calflagins. These proteins associate with lipid raft microdomains in the flagellar membrane, where they putatively function as calcium signaling proteins. Here we show that these proteins bind calci...

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Bibliographic Details
Main Authors: Emmer, Brian T., Daniels, Melvin D., Taylor, Joann M., Epting, Conrad L., Engman, David M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901653/
https://ncbi.nlm.nih.gov/pubmed/20418379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00086-10
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