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Calflagin Inhibition Prolongs Host Survival and Suppresses Parasitemia in Trypanosoma brucei Infection

African trypanosomes express a family of dually acylated, EF-hand calcium-binding proteins called the calflagins. These proteins associate with lipid raft microdomains in the flagellar membrane, where they putatively function as calcium signaling proteins. Here we show that these proteins bind calci...

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Bibliografiske detaljer
Main Authors: Emmer, Brian T., Daniels, Melvin D., Taylor, Joann M., Epting, Conrad L., Engman, David M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901653/
https://ncbi.nlm.nih.gov/pubmed/20418379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00086-10
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