Efficacy of recombinant annexin 2 for fibrinolytic therapy in a rat embolic stroke model: A magnetic resonance imaging study

Efficacy of recombinant annexin 2 (rAN II) in a rat model of embolic stroke was examined using a magnetic resonance imaging (MRI) and histology. The right middle cerebral artery of male Wistar rats was occluded by autologous clots under anesthesia. Four doses of rAN II (0.125, 0.25, 0.5 and 1.0 mg/k...

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Hauptverfasser: Tanaka, Yoji, Ishii, Hideto, Hiraoka, Megumi, Miyasaka, Naoyuki, Kuroiwa, Toshihiko, Hajjar, Katherine A., Nagaoka, Tsukasa, Duong, Timothy Q., Ohno, Kikuo, Yoshida, Masayuki
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900767/
https://ncbi.nlm.nih.gov/pubmed/17651708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2007.06.039
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