Patterns of Human Immunodeficiency Virus Type 1 Recombination Ex Vivo Provide Evidence for Coadaptation of Distant Sites, Resulting in Purifying Selection for Intersubtype Recombinants during Replication

High-frequency recombination is a hallmark of HIV-1 replication. Recombination can occur between two members of the same subtype or between viruses from two different subtypes, generating intra- or intersubtype recombinants, respectively. Many intersubtype recombinants have been shown to circulate i...

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Hauptverfasser: Galli, Andrea, Kearney, Mary, Nikolaitchik, Olga A., Yu, Sloane, Chin, Mario P. S., Maldarelli, Frank, Coffin, John M., Pathak, Vinay K., Hu, Wei-Shau
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Genetic Diversity and Evolution
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897624/
https://ncbi.nlm.nih.gov/pubmed/20504919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00276-10
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