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Impact of Lentiviral Vector-Mediated Transduction on the Tightness of a Polarized Model of Airway Epithelium and Effect of Cationic Polymer Polyethylenimine

Lentiviral (LV) vectors are promising agents for efficient and long-lasting gene transfer into the lung and for gene therapy of genetically determined pulmonary diseases, such as cystic fibrosis, however, they have not been evaluated for cytotoxicity and impact on the tightness of the airway epithel...

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Bibliographic Details
Main Authors: Castellani, Stefano, Di Gioia, Sante, Trotta, Teresa, Maffione, Angela Bruna, Conese, Massimo
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896616/
https://ncbi.nlm.nih.gov/pubmed/20617131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/103976
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