Rosiglitazone Improves Lipoatrophy in Patients Receiving Thymidine-Sparing Regimens

OBJECTIVE: Thymidine reverse transcriptase inhibitors (tNRTI) are strong inhibitors of PPAR-γ and clearly implicated as a cause of lipoatrophy. Thiazolidenediaones (TZD), potent PPAR-γ agonists, would be expected to be beneficial in HIV lipoatrophy, but prior studies have been conflicting. None spec...

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Autors principals: Tungsiripat, Marisa, El Bejjani, Dalia, Rizk, Nezrine, O'Riordan, Mary Ann, Ross, Allison C, Hileman, Corrilynn, Storer, Norma, Harrill, Danielle, McComsey, Grace A
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895409/
https://ncbi.nlm.nih.gov/pubmed/20453626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0b013e328339e274
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