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Tumor-Associated Retinal Astrocytes Promote Retinoblastoma Cell Proliferation Through Production of IGFBP-5

Retinoblastomas consist of cone-like neoplastic cells and diverse non-neoplastic cells whose roles in tumorigenesis have not been defined. Here, we investigated the glial cells that constitute 2% to 3% of the cells in retinoblastoma tumors, including their origin, their relationship to a potential r...

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Detalhes bibliográficos
Main Authors: Xu, Xiaoliang L., Lee, Thomas C., Offor, Nneka, Cheng, Christine, Liu, Aihong, Fang, Yuqiang, Jhanwar, Suresh C., Abramson, David H., Cobrinik, David
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893684/
https://ncbi.nlm.nih.gov/pubmed/20508032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090512
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