miR-107 Regulates Granulin/Progranulin with Implications for Traumatic Brain Injury and Neurodegenerative Disease

Granulin (GRN, or progranulin) is a protein involved in wound repair, inflammation, and neoplasia. GRN has also been directly implicated in frontotemporal dementia and may contribute to Alzheimer’s disease pathogenesis. However, GRN regulation expression is poorly understood. A high-throughput exper...

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Detalhes bibliográficos
Main Authors: Wang, Wang-Xia, Wilfred, Bernard R., Madathil, Sindhu K., Tang, Guiliang, Hu, Yanling, Dimayuga, James, Stromberg, Arnold J., Huang, Qingwei, Saatman, Kathryn E., Nelson, Peter T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893676/
https://ncbi.nlm.nih.gov/pubmed/20489155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.091202
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