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High cell density cultivation and recombinant protein production with Escherichia coli in a rocking-motion-type bioreactor

BACKGROUND: Single-use rocking-motion-type bag bioreactors provide advantages compared to standard stirred tank bioreactors by decreased contamination risks, reduction of cleaning and sterilization time, lower investment costs, and simple and cheaper validation. Currently, they are widely used for c...

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Detalhes bibliográficos
Main Authors: Glazyrina, Julia, Materne, Eva-Maria, Dreher, Thomas, Storm, Dirk, Junne, Stefan, Adams, Thorsten, Greller, Gerhard, Neubauer, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891675/
https://ncbi.nlm.nih.gov/pubmed/20509968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-9-42
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