Pharmacokinetic properties and antitumor efficacy of the 5-fluorouracil loaded PEG-hydrogel

BACKGROUND: We have studied the in vitro and in vivo utility of polyethylene glycol (PEG)-hydrogels for the development of an anticancer drug 5-fluorouracil (5-FU) delivery system. METHODS: A 5-FU-loaded PEG-hydrogel was implanted subcutaneously to evaluate the drug retention time and the anticancer...

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Detalhes bibliográficos
Main Authors: Yi, Hee, Cho, Hee-Jung, Cho, Soo-Min, Lee, Dong-Goo, Abd El-Aty, AM, Yoon, So-Jeong, Bae, Gun-Won, Nho, Kwang, Kim, Bokyung, Lee, Chi-Ho, Kim, Jin-Suk, Bartlett, Michael G, Shin, Ho-Chul
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889891/
https://ncbi.nlm.nih.gov/pubmed/20482808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-211
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