Assessing circadian rhythms in propofol PK and PD during prolonged infusion in ICU patients

This study evaluates possible circadian rhythms during prolonged propofol infusion in patients in the intensive care unit. Eleven patients were sedated with a constant propofol infusion. The blood samples for the propofol assay were collected every hour during the second day, the third day, and afte...

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Hauptverfasser: Bienert, Agnieszka, Kusza, Krzysztof, Wawrzyniak, Katarzyna, Grześkowiak, Edmund, Kokot, Zenon J., Matysiak, Jan, Grabowski, Tomasz, Wolc, Anna, Wiczling, Paweł, Regulski, Miłosz
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889282/
https://ncbi.nlm.nih.gov/pubmed/20544262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10928-010-9161-5
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