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An Overview of APP Processing Enzymes and Products

The generation of amyloid β-peptide (Aβ) by enzymatic cleavages of the β-amyloid precursor protein (APP) has been at the center of Alzheimer’s disease (AD) research. While the basic process of β- and γ-secretase-mediated generation of Aβ is text book knowledge, new aspects of Aβ and other cleavage p...

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Detalhes bibliográficos
Main Authors: Chow, Vivian W., Mattson, Mark P., Wong, Philip C., Gleichmann, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889200/
https://ncbi.nlm.nih.gov/pubmed/20232515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12017-009-8104-z
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