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Synergistic Effects of NAT2 slow and GSTM1 null genotypes on Carcinogen DNA Damage in the Lung

BACKGROUND: Polymorphisms in carcinogen detoxification enzymes, NAT2 and GSTM1, have been suggested as susceptibility factors for DNA damage and lung cancer. However, little information is available on DNA adduct burden in the lung tissue and polymorphisms in NAT2 and GST genes. We investigated the...

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書誌詳細
主要な著者: Lee, Mi-Sun, Su, Li, Christiani, David C.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882986/
https://ncbi.nlm.nih.gov/pubmed/20501762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-09-1195
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