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Caspase Inhibition Modulates Left Ventricular Remodeling Following Myocardial Infarction through Cellular and Extracellular Mechanisms

BACKGROUND: Myocyte death occurs by necrosis and caspase-mediated apoptosis in myocardial infarction (MI). In-vitro studies suggest caspase activation causes myocardial contractile protein degradation without inducing apoptosis. Thus, caspase activation may evoke left ventricular (LV) remodeling thr...

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Bibliografski detalji
Glavni autori: Yarbrough, William M., Mukherjee, Rupak, Stroud, Robert E., Meyer, Evan C., Escobar, G. Patricia, Sample, Jeffrey A., Hendrick, Jennifer W., Mingoia, Joseph T., Spinale, Francis G.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880531/
https://ncbi.nlm.nih.gov/pubmed/20147844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0b013e3181d4ca66
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