Alternative splicing of human papillomavirus type-16 E6/E6* early mRNA is coupled to EGF signaling via Erk1/2 activation

Certain types of human papillomaviruses (HPVs) are etiologically linked to cervical cancer. Their transforming capacity is encoded by a polycistronic premRNA, where alternative splicing leads to the translation of functional distinct proteins such as E6, E6*, and E7. Here we show that splicing of HP...

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Detalhes bibliográficos
Main Authors: Rosenberger, Simone, Arce, Johanna De-Castro, Langbein, Lutz, Steenbergen, Renske D. M., Rösl, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872467/
https://ncbi.nlm.nih.gov/pubmed/20351270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1002620107
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