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Inhibition of Histone Deacetylase Expands the Renal Progenitor Cell Population

One of the first hallmarks of kidney regeneration is the reactivation of genes normally required during organogenesis. Identification of chemicals with the potential to enhance this reactivation could therapeutically promote kidney regeneration. Here, we found that 4-(phenylthio)butanoic acid (PTBA)...

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Autori principali: de Groh, Eric D., Swanhart, Lisa M., Cosentino, Chiara Cianciolo, Jackson, Rachel L., Dai, Weixiang, Kitchens, Carolyn A., Day, Billy W., Smithgall, Thomas E., Hukriede, Neil A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Nephrology 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865739/
https://ncbi.nlm.nih.gov/pubmed/20378823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009080851
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