TCEAL7 Inhibition of c-Myc Activity in Alternative Lengthening of Telomeres Regulates hTERT Expression

Replicative senescence forms a major barrier to tumor progression. Cancer cells bypass this by using one of the two known telomere maintenance mechanisms: telomerase or the recombination-based alternative lengthening of telomeres (ALT) mechanism. The molecular details of ALT are currently poorly und...

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Hlavní autoři: Lafferty-Whyte, Kyle, Bilsland, Alan, Hoare, Stacey F, Burns, Sharon, Zaffaroni, Nadia, Cairney, Claire J, Keith, William Nicol
Médium: Artigo
Jazyk:Inglês
Vydáno: Neoplasia Press Inc. 2010
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864478/
https://ncbi.nlm.nih.gov/pubmed/20454512
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