Ligand-induced nuclear translocation of S1P(1) Cyr61 and CTGF transcription in endothelial cells

Sphingosine-1-phosphate (S1P) receptor subtype 1 (S1P(1)), a G-protein coupled receptor (GPCR), regulates many biological activities of endothelial cells (ECs). In this report, we show that S1P(1) receptors are present in the nuclei of ECs by using various biochemical and microscopic techniques such...

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Bibliografiske detaljer
Main Authors: Estrada, Rosendo, Wang, Lichun, Jala, Venkatakrishna R., Lee, Jen-Fu, Lin, Cheng-Yon, Gray, Robert D., Haribabu, Bodduluri, Lee, Menq-Jer
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861785/
https://ncbi.nlm.nih.gov/pubmed/18936953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00418-008-0521-9
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