Ligand-induced nuclear translocation of S1P(1) Cyr61 and CTGF transcription in endothelial cells

Sphingosine-1-phosphate (S1P) receptor subtype 1 (S1P(1)), a G-protein coupled receptor (GPCR), regulates many biological activities of endothelial cells (ECs). In this report, we show that S1P(1) receptors are present in the nuclei of ECs by using various biochemical and microscopic techniques such...

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Detalhes bibliográficos
Main Authors: Estrada, Rosendo, Wang, Lichun, Jala, Venkatakrishna R., Lee, Jen-Fu, Lin, Cheng-Yon, Gray, Robert D., Haribabu, Bodduluri, Lee, Menq-Jer
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861785/
https://ncbi.nlm.nih.gov/pubmed/18936953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00418-008-0521-9
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