Ligand-induced nuclear translocation of S1P(1) Cyr61 and CTGF transcription in endothelial cells

Sphingosine-1-phosphate (S1P) receptor subtype 1 (S1P(1)), a G-protein coupled receptor (GPCR), regulates many biological activities of endothelial cells (ECs). In this report, we show that S1P(1) receptors are present in the nuclei of ECs by using various biochemical and microscopic techniques such...

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Autori principali: Estrada, Rosendo, Wang, Lichun, Jala, Venkatakrishna R., Lee, Jen-Fu, Lin, Cheng-Yon, Gray, Robert D., Haribabu, Bodduluri, Lee, Menq-Jer
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861785/
https://ncbi.nlm.nih.gov/pubmed/18936953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00418-008-0521-9
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