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Glutathione s-transferase polymorphisms are associated with survival in anaplastic glioma patients

BACKGROUND: Glutathione S-transferases (GST) are polymorphic enzymes responsible for glutathione conjugation of alkylators and scavenging of free radicals created by radiation. GST polymorphisms may result in altered or absent enzyme activity and have been associated with survival in patients with c...

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Autors principals: Kilburn, Lindsay, Okcu, M. Fatih, Wang, Tao, Cao, Yumei, Renfro-Spelman, Amy, Aldape, Kenneth D., Gilbert, Mark R., Bondy, Melissa
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861043/
https://ncbi.nlm.nih.gov/pubmed/20187096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.25006
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