Loss of fibulin-5 binding to β1 integrins inhibits tumor growth by increasing the level of ROS

Tumor survival depends in part on the ability of tumor cells to transform the surrounding extracellular matrix (ECM) into an environment conducive to tumor progression. Matricellular proteins are secreted into the ECM and impact signaling pathways that are required for pro-tumorigenic activities suc...

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Bibliographische Detailangaben
Hauptverfasser: Schluterman, Marie K., Chapman, Shelby L., Korpanty, Grzegorz, Ozumi, Kiyoshi, Fukai, Tohru, Yanagisawa, Hiromi, Brekken, Rolf A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Limited 2010
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860852/
https://ncbi.nlm.nih.gov/pubmed/20197418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.003707
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