Spironolactone and hydrochlorothiazide exert antioxidant effects and reduce vascular matrix metalloproteinase-2 activity and expression in a model of renovascular hypertension

BACKGROUND AND PURPOSE: Increased oxidative stress and up-regulation of matrix metalloproteinases (MMPs) may cause structural and functional vascular changes in renovascular hypertension. We examined whether treatment with spironolactone (SPRL), hydrochlorothiazide (HCTZ) or both drugs together modi...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Ceron, CS, Castro, MM, Rizzi, E, Montenegro, MF, Fontana, V, Salgado, MCO, Gerlach, RF, Tanus-Santos, JE
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2010
Fag:
Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860208/
https://ncbi.nlm.nih.gov/pubmed/20331602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.00678.x
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker