In vitro and in vivo protective efficacies of antibodies that neutralize the RNA N-glycosidase activity of Shiga toxin 2

BACKGOUND: Shiga toxin 2 (Stx2), one of two Stx liberated by Stx-producing Escherichia coli, is composed of an A subunit monomer and a B subunit pentamer, and is directly linked with hemolytic uremic syndrome in children. The pentameric B subunit binds to its cell surface receptor Gb(3 )for toxin in...

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Detaylı Bibliyografya
Asıl Yazarlar: Jeong, Kwang-il, Chapman-Bonofiglio, Susan, Singh, Pradeep, Lee, Jongo, Tzipori, Saul, Sheoran, Abhineet S
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2010
Konular:
Research article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859748/
https://ncbi.nlm.nih.gov/pubmed/20334660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-11-16
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