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Common Variant in GRN Is a Genetic Risk Factor for Hippocampal Sclerosis in the Elderly

BACKGROUND: Hippocampal sclerosis (HpScl) is common in elderly subjects with dementia, either alone or accompanied by other pathologic processes. It is also found in >70% of frontotemporal lobar degeneration with TDP-43 immunoreactive inclusions (FTLD-TDP). TDP-43 inclusions are detected in >2...

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Detalhes bibliográficos
Main Authors: Dickson, Dennis W., Baker, Matthew, Rademakers, Rosa
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859236/
https://ncbi.nlm.nih.gov/pubmed/20197700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000289231
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